Non-malignant lesions; clinico-pathological profile of nasal cavity and paranasal sinuses

The presence of a mass in the nasal cavity and paranasal sinuses may seem to be simple problem, but it is very difficult to differentiate clinically from potentially malignant tumors. To evaluate the clinical presentation and histopathological features of the non malignant lesions of nasal cavity and paranasal sinuses. Prospective descriptive study. Study was carried out in departments of Paediatrics and ENT at Ghulam Muhammad Mahar Medical College Hospital Sukkur from Jan 2009 to Dec 2012. The study included all cases of nonmalignant masses of nasal cavity and paranasal sinuses, those attended the Paediatric and ENT department and underwent the surgical intervention. One hundred twenty non-malignant cases were enrolled for this study. A separate pro-forma was filled to record the cases biodata, history, clinical examination, investigations and histopathological diagnosis. All histopathologically proven malignant masses were excluded from the study. Out of 120 cases 78 [65%] were males and 42 [35%] were females, with M:F ratio of 1.8:1. The age of presentation ranged from 8 years to 70 years and mean age was 26.3years. Sinonasal masses were found to be bilateral in 20 cases [16.67%], right sided in 65 [54.17%] and left sided in 35 [29.16%] cases. The main presenting symptoms were nasal blockage 110 [91.66%], nasal discharge 102 [85%], sneezing 60 [50%], hypoinsomnia 36 [30%], epistaxis 24 [20%], headache 20 [18.33%] and mouth breathing 18 [15%] cases. Polyp was the most common lesion in 86 [71.66%] cases observed in this study. The common histopathological diagnosis was simple inflammatory nasal polyp in 48 [40%], allergic nasal polyps 30 [25%] and fibroepithelial polyp in 8 [6.7%], inverted papilloma in 12 [10%], angiofibroma 6 [5%], capillary hemangioma 4 [3.34%] and rhinosporidiosis 4 [3.34%] cases. Sinonasal masses have various differential diagnoses and are still thought to be simple problem in our society. There is a need for early recognition and referral to ENT surgeon and need histopathological examination of every mass to confirm the diagnosis

Intraoperative findings during canal wall down mastoidectomy in chronic suppurative otitis media at a tertiary care hospital, Sukkur, Pakistan

To assess the intraoperative findings during canal wall down mastoidectomy in patients for unsafe type of chronic suppurative otitis media [CSOM]. This prospective interventional study was carried out at Department of ENT and Pediatrics of Ghulam Muhammad Mahar Medical College Hospital, Sukkur, Pakistan from June 2009 to June 2011. Eighty patients who were 5-55 years of age, of both genders, with CSOM who underwent canal wall down mastoidectomy were included in the study. The operative findings like extent of cholesteatoma, granulation tissue in different location in middle ear cleft and ossicular chain condition and otogenic complication were identified. Females were affected more than males [n=48; 60%]. Granulation tissue was found in 50 [62.5%] of cases, while cholesteatoma in 30 [37.5%] cases. The extent of disease was attic in 4 [5%], attic and middle ear 30 [37.5%], attic and antrum 16 [20%] and attic, antrum and middle ear 30 [37%] patients. In majority of the cases there were involvement of more than one ossicle; among the most affected single ossicle malleus was found necrosed in 50 [62.5%], and absent in 6 [7.5%] cases, incus was found necrosed in 42 [52.5%], and stapes was found necrosed in 20 [25%] of cases. The primary disease found in our patients undergoing canal wall down mastoidectomy was granulation. Less common were cholesteatoma and multi-ossicular

presentation of carcinoma of larynx at civil hospital Karachi

To determine the frequency of different presenting clinical features and the most common stage of presentation in patients of laryngeal carcinoma. Descriptive study. This study was conducted at ENT department, Dow University of Health Sciences and Civil Hospital Karachi, from April 2006 to March 2007. All the patients of biopsy proven laryngeal carcinoma of any age and sex were included in the study. Demographic data, presenting complain like change in voice, difficulty in breathing, difficulty in swallowing, pain, smoked and unsmoked tobacco use, clinical examination findings, DL findings, neck examination with respect to levels of lymph nodes involvement, presence or absence of metastasis recorded in performed proforma. Histopathological reports and findings of imaging studies like X-ray chest, CT scan, and ultrasound abdomen [if needed], stage of carcinoma larynx were also recorded on proforma. In this study out of 34 cases, 32 [94.1%] were males and only 2 [5.88%] were females. Mean age was 55.23 years [SD +/- 12.09]. Most common symptom was hoarseness in 32 [94.1%] cases, 27 [79.4%] presented at advanced stage [stage III and IV] while commonest site was glottic region 50%. This study concluded that the most common stage of laryngeal carcinoma patients in our setup was late stage and commonest presenting symptom was hoarseness while commonest site was glottic region

Xeroderma pigmentosa - squamous cell carcinoma lip

A 10 Years old female patient of xeroderma pigmentosa [XP] presented with an oval shaped swelling on left upper lip for 2 months. Excisional biopsy was done and histopathology revealed moderately differentiated Squamous cell carcinoma. We report this case as Xeroderma pigmentosa with squamous cell carcinoma is rarely seen in ENT practice